Same here. Luckily I found a quick fix I thought I’d share with you guys.
Run the following in Terminal:
sudo apt-get install gnome-alsamixer
After install, open up the app from Applications>Sound and Video, and just unmute everything (as well as sliding up the volume) on both tabs.
And your sound should work as normal!
You know those kernel updates and such like that force you to restart your always-on system, interrupting your geek-a-thon? Yeah, I hate them too.

Well here comes KSplice, that fixes that problem. It allows you to install any update without restarting your system.

Download a .deb for Karmic or Jaunty here.
It will auto-start and sit in the panel and notify you when any kernel updates are available.
It does not automatically create a menu entry, so if you wish to restart it (or start it again after quitting), run the following command in the terminal:
uptrack-manager
Of course you can create an entry in the GNOME menu by going to System>Preferences>Main Menu>Add Entry and in the command field entering the one above.
Please note that you can only install kernel updates in KSplice, and must install any others in the regular Update Manager.
One of the first things I do after a fresh install of Ubuntu is install Ubuntu Tweak, a great tweaking and management tool.
Today the new version- 0.4.9.2 -has been released and announced on the creator’s blog.
What’s new:
New PPA’s
- Gartoon Redux icon theme
- Gnome Music Player Client
- Mingming’s PPA (Flash plugin [inc. 64bit!], + lots of libs)
- Rico Tzschichholz’s PPA (Gnome-Shell, Docky, Inkscape)
Updated Third-Party Sources
- osd-lyrics
- Dropbox
- Amarok
- Blueman
- Christine
- Smplayer
- PlayOnLinux
- XMBC
- Vlc
- Clutter
- Gloobus
- Bisigi
Sources Removed
- Ubuntu-CN
- Transmission daily
Bug Fixed
- Personal>Folder menu error on opening (LP: #461666)
A new “Theme” sub menu has been introduced so you can install even more themes: -

Download
You’ll automatically receive the update if you already have a previous version installed, if not download a deb here.
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He also gave us a preview of the next version, 0.5:

New Features Include:
- One package for all architectures
- New UI
- All icons native (meaning they match you’re theme)
- New website
Looking forward to it!
You know the really nice font used in the Ubuntu logo? Yeah, this one:

I’m sure many of you have been tearing your hair out trying to find out what it is; well no more!
Run this in terminal to install the beauty:
sudo apt-get install ttf-ubuntu-title
Easy Peasy.